Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2005;9(6):647-8.
doi: 10.1186/cc3951. Epub 2005 Nov 23.

Goal directed therapy: how long can we wait?

Anthony C Gordon  1 , James A Russell
Affiliations
Comment

Goal directed therapy: how long can we wait?

Anthony C Gordon et al. Crit Care. 2005.

Abstract

Intensive monitoring and aggressive management of perioperative haemodynamics (goal directed therapy) have repeatedly been reported to reduce the significant morbidity and mortality associated with high risk surgery. It may not matter what particular monitor is used to assess cardiac output but it is essential to ensure adequate oxygen delivery. If this management cannot begin preoperatively, it is still worth beginning goal directed therapy in the immediate postoperative period.

PubMed Disclaimer

Comment on

References

    1. Pearse R, Dawson D, Fawcett J, Rhodes A, Grounds M, Bennett D. Early goal-directed therapy after major surgery reduces complications and duration of hospital stay. A randomised, controlled trial [ISRCTN38797445] Crit Care. 9:R687–R693. doi: 10.1186/cc3887. - DOI - PMC - PubMed
    1. Pearse R, Dawson D, Fawcett J, Rhodes A, Grounds M, Bennett D. Changes in central venous saturation following major surgery, and association with outcome. Crit Care. 9:R694–R699. doi: 10.1186/cc3888. - DOI - PMC - PubMed
    1. Boyd O, Grounds RM, Bennett ED. A randomized clinical trial of the effect of deliberate perioperative increase of oxygen delivery on mortality in high-risk surgical patients. J Am Med Assoc. 1993;270:2699–2707. doi: 10.1001/jama.270.22.2699. - DOI - PubMed
    1. Shoemaker W, Appel P, Kram H, Waxman K, Lee T. Prospective trial of supranormal values of survivors as therapeutic goals in high-risk surgical patients. Chest. 1988;94:1176–1186. - PubMed
    1. Wilson J, Woods I, Fawcett J, Whall R, Dibb W, Morris C, McManus E. Reducing the risk of major elective surgery: randomised controlled trial of preoperative optimisation of oxygen delivery. Br Med J. 1999;318:1099–1103. - PMC - PubMed

Publication types