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Comparative Study
. 2005 Dec;147(6):860-2.
doi: 10.1016/j.jpeds.2005.07.032.

Male/female differences in indomethacin effects in preterm infants

Arne Ohlsson  1 , Robin S Roberts, Barbara Schmidt, Peter Davis, Diane Moddeman, Saroj Saigal, Alfonso Solimano, Michael Vincer, Linda Wright; Trial Of Indomethacin Prophylaxis In Preterms Tipp Investigators
Affiliations
Comparative Study

Male/female differences in indomethacin effects in preterm infants

Arne Ohlsson et al. J Pediatr. 2005 Dec.

Abstract

To test whether indomethacin prophylaxis has sex-mediated effects on severe intraventricular hemorrhage (grade III and IV) and on long-term outcomes in extremely-low-birth-weight infants. A secondary analysis was performed in the entire "Trial of Indomethacin Prophylaxis in Preterms study" cohort. The results suggest a weak differential treatment effect of indomethacin by sex.

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