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. 2006 Feb;47(2):156-62.
doi: 10.1016/j.toxicon.2005.10.013. Epub 2005 Dec 13.

First report on cylindrospermopsin producing Aphanizomenon flos-aquae (Cyanobacteria) isolated from two German lakes

Karina Preussel  1 , Anke Stüken, Claudia Wiedner, Ingrid Chorus, Jutta Fastner
Affiliations

First report on cylindrospermopsin producing Aphanizomenon flos-aquae (Cyanobacteria) isolated from two German lakes

Karina Preussel et al. Toxicon. 2006 Feb.

Abstract

Three single-filament isolates of Aphanizomenon flos-aquae from two German lakes were found to produce remarkable amounts of the cyanobacterial hepatotoxin cylindrospermopsin (CYN). CYN-synthesis of the strains were evidenced both by LC-MS/MS analysis and detection of PCR products of gene fragments which are implicated in the biosynthesis of the toxin. The strains contain CYN in the range of 2.3-6.6 mg g(-1) of cellular dry weight. To our knowledge this is the first report of CYN in A. flos-aquae.

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