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. 1992 Feb 17;136(1):67-71.
doi: 10.1016/0304-3940(92)90649-r.

Expression of GAD mRNA in GABA interneurons of the rat medial frontal cortex

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Expression of GAD mRNA in GABA interneurons of the rat medial frontal cortex

S Rétaux et al. Neurosci Lett. .

Abstract

The distribution of glutamic acid decarboxylase (GAD) mRNA containing cells was studied in the rat medial frontal cortex (MFC). The neurons labelled by the 35S-labelled cDNA probe were distributed uniformly throughout all the layers and represented 16% of the total neuronal population. It was possible to distinguish two cell populations expressing high and low levels of GAD mRNA corresponding to 63% and 27% of labelled cells, respectively. Concerning the laminar distribution of these two populations of GAD mRNA containing neurons, no marked difference was observed between the various areas of the MFC.

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