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Review
. 2006 Feb;17(1):99-109.
doi: 10.1016/j.semcdb.2005.11.008. Epub 2005 Dec 13.

Transcriptional regulation of mesendoderm formation in Xenopus

Fiona C Wardle  1 , James C Smith
Affiliations
Review

Transcriptional regulation of mesendoderm formation in Xenopus

Fiona C Wardle et al. Semin Cell Dev Biol. 2006 Feb.

Abstract

Mesoderm and endoderm formation in Xenopus involves the coordinated efforts of maternally and zygotically expressed transcription factors together with growth factor signalling, including members of the TGFbeta and wnt families. In this review we discuss our current state of knowledge of these pathways, and describe in more detail some of the transcription factor-DNA interactions that are involved in mesendoderm formation.

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