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Comment
. 2005 Dec;23(6):551-3.
doi: 10.1016/j.immuni.2005.11.007.

Phosphorylation of CARMA1: the link(er) to NF-kappaB activation

Daniel Rueda  1 , Margot Thome
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Free article
Comment

Phosphorylation of CARMA1: the link(er) to NF-kappaB activation

Daniel Rueda et al. Immunity. 2005 Dec.
Free article

Abstract

Antigen receptor-induced NF-kappaB activation depends on receptor-proximal and -distal signaling events. Two papers in this issue of Immunity demonstrate that PKC-dependent phosphorylation of CARMA1 is the critical molecular link that controls the activation of the IKK signalosome and NF-kappaB.

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