Poxviruses aren't stuPYD
- PMID: 16356854
- DOI: 10.1016/j.immuni.2005.11.008
Poxviruses aren't stuPYD
Abstract
Pathogens utilize many strategies to dampen the host inflammatory response. In this issue of Immunity, a report by Johnston and colleagues reveals a poxvirus strategy that inhibits the inflammasome, arresting secretion of interleukin-1-related cytokines, thus silencing key alarms that mobilize host defenses.
Comment on
-
A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infection.Immunity. 2005 Dec;23(6):587-98. doi: 10.1016/j.immuni.2005.10.003. Immunity. 2005. PMID: 16356857
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
