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Review
. 2006 Jan;5(2):172-5.
doi: 10.4161/cc.5.2.2343. Epub 2006 Jan 16.

The MicroRNA pathway plays a regulatory role in stem cell division

H R Shcherbata  1 , S Hatfield, E J Ward, S Reynolds, K A Fischer, H Ruohola-Baker
Affiliations
Review

The MicroRNA pathway plays a regulatory role in stem cell division

H R Shcherbata et al. Cell Cycle. 2006 Jan.

Abstract

One of the key characteristics of stem cells is their capacity for self-renewal for long periods of time. In this respect, stem cells are similar to cancer cells, which also have the ability to escape cell cycle stop signals. Therefore, a critical question in stem cell and cancer biology is how cell division is regulated in these cell types. In this review, we summarize recent progress and describe future challenges to understanding the role the microRNA pathway plays in regulating mechanisms controlling stem cell division.

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