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. 2006 Jan 7;4(1):36-7.
doi: 10.1039/b513113h. Epub 2005 Nov 22.

Mitsunobu dehydration of N-Boc neomycin B

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Mitsunobu dehydration of N-Boc neomycin B

Sabina Quader et al. Org Biomol Chem. .

Abstract

Reaction of hexa-N-Boc neomycin B with TPP and DIAD in toluene results in the formation of an epoxide in ring IV, not an aziridine or azetidine as previously reported.

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