Review
doi: 10.1111/j.1365-2559.2005.02286.x.
The role of microarray technologies in the study of soft tissue tumours
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- PMID: 16359534
- DOI: 10.1111/j.1365-2559.2005.02286.x
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Review
The role of microarray technologies in the study of soft tissue tumours
Histopathology.
2006 Jan.
Abstract
Array technologies (gene array, tissue microarray and others) are being used in a growing number of research projects involving soft tissue tumours. Gene array techniques allow for measurements of RNA expression levels or gene copy number changes for a large number of genes in a single specimen. A complementary technique, tissue microarrays, allows for the measurement of expression of a single gene in a large number of specimens. These techniques and similar ones have created a fundamentally new approach to the investigation of soft tissue tumours. This review addresses some of the advantages, problems, and solutions to those problems that come with these technologies.
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