Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2005 Dec;30(12):1501-10.
doi: 10.1007/s11064-005-8827-7.

Problems associated with biological markers of Alzheimer's disease

H J Frey  1 , K M Mattila, M A Korolainen, T Pirttilä
Affiliations

Problems associated with biological markers of Alzheimer's disease

H J Frey et al. Neurochem Res. 2005 Dec.

Abstract

The etiopathogenesis of Alzheimer's disease (AD) is still unclear, although clinical diagnostic criteria exist and the neuropathology of AD has been studied in great detail during the last 20 years. The present study addresses certain problems in the search for biological markers for the diagnosis, as well as in the follow-up of the course of AD and its differential diagnosis and reports some of our own observations in comparison with other studies. These include protein, genetic and neuroimaging markers. The definitions of biological markers and search strategies are also discussed.

PubMed Disclaimer

References

    1. Pathol Biol (Paris). 1996 Oct;44(8):685-8 - PubMed
    1. Clin Chim Acta. 2003 Mar;329(1-2):23-38 - PubMed
    1. Neurobiol Aging. 2005 May;26(5):581-3 - PubMed
    1. Neurobiol Aging. 1997 Jul-Aug;18(4 Suppl):S1-2 - PubMed
    1. Neurobiol Aging. 2004 Jan;25(1):105-10 - PubMed

LinkOut - more resources