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. 2005 Dec 28;127(51):18002-3.
doi: 10.1021/ja0552500.

Gold(I)-catalyzed stereoselective olefin cyclopropanation

Magnus J Johansson  1 , David J Gorin, Steven T Staben, F Dean Toste
Affiliations

Gold(I)-catalyzed stereoselective olefin cyclopropanation

Magnus J Johansson et al. J Am Chem Soc. .

Abstract

A triphenylphosphinegold(I)-catalyzed cyclopropanation of olefins using propargyl esters as gold(I)-carbene precursors is reported. This reaction provided the basis for the use of a DTBM-SEGPHOS gold(I) complex as a catalyst in the enantioselective (up to 94% ee) preparation of vinyl cyclopropanes with high cis-selectivity.

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