[Predictor of early thrombolysis in acute coronary syndrome by estimation of the QT interval variability on 12 lead standard electrocardiogram]

Abstract

It has been stated that decreased dispersion of QT interval (QTd) on 12 lead ECG is associated with successful thrombolysis (TH) in acute myocardial infarction but it is not clear whether QTd can predict early successful TH. The goal of the investigation was to evaluate significance of QTd and QT interval variability between adjacent precordial leads (QTdl) for prediction of successful early TH in acute coronary syndrome (ACS). Two groups of patients after 6 hours from the beginning of acute coronary attack with elevation of ST segment on ECG were under investigation: I group -- 26 patients with resolution of ST> or =70% after 60-90 min from the starting of TH and II group -- 21 patients with no resolution of ST. QTd was defined as the difference between maximal and minimal QT interval and QTd as the difference between adjacent precordial ECG leads. QTd is a marker of successful TH but does not predict its efficiency, QTde<50 predicted TH with 80% sensitivity, 85% specificity and 87% positive predictive value.