Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2001 Jan;14(1):8-12.
doi: 10.1080/08998280.2001.11927724.

Sarcoidosis: still a mystery?

T B Pierce  1 , M Margolis, M A Razzuk
Affiliations

Sarcoidosis: still a mystery?

T B Pierce et al. Proc (Bayl Univ Med Cent). 2001 Jan.

Abstract

Sarcoidosis is a systemic granulomatous disease of unknown etiology. It has diverse clinical manifestations, most frequently including pulmonary disorders. It is associated with immunological abnormalities, the intricacies of which have yet to be clearly delineated. In the immunologically susceptible individual, genetic, environmental, nutritional, and socioeconomic factors may play a governing role in its development. Sarcoidosis is a diagnosis of exclusion established by clinical manifestations, radiologic findings, and histologic evidence of noncaseating epithelioid-cell granulomas in >1 organ. We will discuss parameters that are helpful in making this diagnosis.

PubMed Disclaimer

References

    1. Sharma O. Sarcoidosis: A Clinical Approach. Springfield, IL: Charles C Thomas; 1975. History; p. 1.
    1. Sarno M, Hasleton PS, Spiteri M. Sarcoidosis. In: Hasleton PS, editor. Spencer's Pathology of the Lung. 5th ed. New York: McGraw-Hill; 1996. pp. 507–535.
    1. Wong CF, Yew WW, Wong PC, Lee J. A case of concomitant tuberculosis and sarcoidosis with mycobacterial DNA present in the sarcoid lesion. Chest. 1998;114:626–629. - PubMed
    1. Priestley S, Delaney JC. Familial sarcoidosis presenting with stridor. Thorax. 1981;36:636–637. - PMC - PubMed
    1. Kremer JM. Histologic findings in siblings with acute sarcoid arthritis: association with the B8,DR3 phenotype. J Rheumatol. 1986;13:593–597. - PubMed

LinkOut - more resources