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. 2005 Dec;10(6):411-7.
doi: 10.1007/s10147-005-0524-7.

Anxiety, depression and quality of life in colorectal cancer patients

Akira Tsunoda  1 , Kentaro Nakao, Kenshi Hiratsuka, Naokuni Yasuda, Miki Shibusawa, Mitsuo Kusano
Affiliations

Anxiety, depression and quality of life in colorectal cancer patients

Akira Tsunoda et al. Int J Clin Oncol. 2005 Dec.

Abstract

Background: Few studies have examined psychological distress and its relationship with quality of life (QL) dimensions in colorectal cancer patients.

Methods: One hundred and twenty-eight outpatients were given psychological tests for anxiety and depression (Hospital Anxiety and Depression Scale; HADS) and QL The European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire C30 (EORTC QLQ-C30) on the same occasion. The association between the patients' emotional function (EF) scoring on EORTC QLQ-C30 and their HADS scores was analyzed by multiple linear regression.

Results: Statistically significant negative relationships were found between EF and HADS-A (anxiety), HADS-D (depression), and HADS-T (total score), respectively, with the highest correlation coefficient being for HADS-A. However, HADS-D was significantly more highly correlated than HADS-A to other QL dimensions, and depression was more highly correlated than anxiety with reduced QL.

Conclusion: The EF dimension of the EORTC QLQ-C30 predominantly assesses anxiety. Depression has a stronger impact on the global QL of patients than anxiety; therefore, the use of an additional instrument is recommended for the assessment of depression in outpatients with colorectal cancer.

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