Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2006 Jan;91(1):F72-4.
doi: 10.1136/adc.2005.074963.

Unnatural selection: reducing antibiotic resistance in neonatal units

Affiliations
Review

Unnatural selection: reducing antibiotic resistance in neonatal units

D Isaacs. Arch Dis Child Fetal Neonatal Ed. 2006 Jan.

Abstract

Antibiotic use selects for antibiotic resistant bacteria. This is an example of rapid Darwinian natural selection in action. It occurs in neonatal intensive care units with the use of parenteral antibiotics, and in the community with oral antibiotic use. A 10 point plan is put forward to reduce antibiotic resistance in neonatal units.

PubMed Disclaimer

Conflict of interest statement

Competing interests: none declared

References

    1. de Man P, Verhoeven B A, Verbrugh H A.et al An antibiotic policy to prevent emergence of resistant bacilli. Lancet 2000355973–978. - PubMed
    1. Goossens H, Ferech M, Stichele R V.et al Outpatient antibiotic use in Europe and association with resistance: a cross‐national database study. Lancet 2005365579–587. - PubMed
    1. Turnidge J, Christiansen K. Antibiotic use and resistance: proving the obvious. Lancet 2005365548–549. - PubMed
    1. Gordon A, Isaacs D. Late onset infection and the role of antibiotic prescribing policies. Curr Opin Infect Dis 200417231–236. - PubMed
    1. Stone P W, Gupta A, Loughrey M.et al Attributable cost and length of stay of an extended‐spectrum beta‐lactamase‐producing Klebsiella pneumoniae outbreak in a neonatal intensive care unit. Infect Control Hosp Epidemiol 200324601–606. - PubMed

MeSH terms

Substances