Gene therapy in sport

Affiliations

¹ Department of Molecular and Clinical Genetics, Royal Prince Alfred Hospital in the Central Clinical School, University of Sydney, NSW, Australia. rtrent@med.usyd.edu.au

R J Trent et al. Br J Sports Med. 2006 Jan.

. 2006 Jan;40(1):4-5.

doi: 10.1136/bjsm.2005.021709.

¹ Department of Molecular and Clinical Genetics, Royal Prince Alfred Hospital in the Central Clinical School, University of Sydney, NSW, Australia. rtrent@med.usyd.edu.au

Abstract

The potential benefits of gene therapy for sports injuries are counterbalanced by the potential for gene doping

Competing interests: none declared

1. Gene therapy clinical trials worldwide http://www.wiley.co.uk/genmed/clinical (accessed 19 Oct 2005)
1. Cavazzana‐Calvo M, Hacein‐Bey S, de Saint Basile G.et al Gene therapy of human severe combined immunodeficiency (SCID)‐X1 disease. Science 2000288669–672. - PubMed
1. Aiuti A, Vai S, Mortellaro A.et al Immune reconstitution in ADA‐SCID after PBL gene therapy and discontinuation of enzyme replacement. Nat Med 20028423–425. - PubMed
1. DelloRusso C, Scott J M, Hartigan‐O'Connor D.et al Functional correction of adult mdx mouse muscle using gutted adenoviral vectors expressing full‐length dystrophin. Proc Natl Acad Sci USA 20029912979–12984. - PMC - PubMed
1. NASA Exploration Systems Mission Directorate Education Outreach http://weboflife.nasa.gov/currentResearch/currentResearchFlight/geneTher... (accessed 19 Oct 2005)