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Case Reports
. 2006 Feb;25(2):232-4.
doi: 10.1097/01.ico.0000179931.05275.dd.

Corneal ulceration and perforation with ketorolac tromethamine (Acular) use after PRK

Shahzad I Mian  1 , Anjali Gupta, Roberto Pineda 2nd
Affiliations
Case Reports

Corneal ulceration and perforation with ketorolac tromethamine (Acular) use after PRK

Shahzad I Mian et al. Cornea. 2006 Feb.

Abstract

Purpose: To report a case of corneal ulceration and perforation after PRK connected with high doses of ketorolac tromethamine (Acula).

Methods: A 31-year-old man presented 5 days after PRK in the left eye with corneal ulceration and perforation requiring penetrating keratoplasty. The patient admitted to using Acular every hour, ciprofloxocin every hour, and prednisolone acetate 1% QID postoperatively.

Results: Laboratory tests, including corneal cultures, were normal. A diagnosis of corneal ulceration secondary to incorrect use of high-dose ketorolac tromethamine was made.

Conclusion: Judicious patient counseling is recommended when using topical NSAIDs in the setting of PRK.

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