doi: 10.1016/0003-9861(92)90658-j.
beta-Carotene and alpha-tocopherol are synergistic antioxidants
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- PMID: 1637180
- DOI: 10.1016/0003-9861(92)90658-j
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beta-Carotene and alpha-tocopherol are synergistic antioxidants
Arch Biochem Biophys.
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Abstract
The possibility of a cooperative interaction between fat-soluble antioxidants is examined in a membrane model. A combination of beta-carotene and alpha-tocopherol results in an inhibition of lipid peroxidation significantly greater than the sum of the individual inhibitions. Our data provide the first evidence that beta-carotene can act synergistically with alpha-tocopherol as an effective radical-trapping antioxidant in membranes.
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