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. 2005 Dec;19(12):1069-70.
doi: 10.1002/ptr.1765.

Antiviral properties of ent-labdene diterpenes of Andrographis paniculata nees, inhibitors of herpes simplex virus type 1

C Wiart  1 , K Kumar, M Y Yusof, H Hamimah, Z M Fauzi, M Sulaiman
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Antiviral properties of ent-labdene diterpenes of Andrographis paniculata nees, inhibitors of herpes simplex virus type 1

C Wiart et al. Phytother Res. 2005 Dec.

Abstract

Andrographolide, neoandrographolide and 14-deoxy-11,12-didehydroandrographolide, ent-labdene diterpenes isolated from Andrographis paniculata showed viricidal activity against herpes simplex virus 1 (HSV-1). None of these compounds exhibited significant cytotoxicity at viricidal concentrations.

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