Role of the aldosterone-sensitive distal nephron in the sodium retention associated with liver cirrhosis
- PMID: 16374415
- DOI: 10.1038/sj.ki.5000095
Role of the aldosterone-sensitive distal nephron in the sodium retention associated with liver cirrhosis
Abstract
The renal mechanisms underlying sodium retention during liver cirrhosis have been difficult to elucidate. Kim and associates describe a biphasic pattern of regulation of the renal epithelial sodium channel in the common bile duct ligation model, shedding some light on this issue.
Comment on
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Biphasic changes of epithelial sodium channel abundance and trafficking in common bile duct ligation-induced liver cirrhosis.Kidney Int. 2006 Jan;69(1):89-98. doi: 10.1038/sj.ki.5000018. Kidney Int. 2006. PMID: 16374428
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