NMR characterization of kinase p38 dynamics in free and ligand-bound forms
- PMID: 16374788
- DOI: 10.1002/anie.200502770
NMR characterization of kinase p38 dynamics in free and ligand-bound forms
Similar articles
-
Computational sampling of a cryptic drug binding site in a protein receptor: explicit solvent molecular dynamics and inhibitor docking to p38 MAP kinase.J Mol Biol. 2006 May 26;359(1):202-14. doi: 10.1016/j.jmb.2006.03.021. Epub 2006 Mar 29. J Mol Biol. 2006. PMID: 16616932
-
Discovery and design of benzimidazolone based inhibitors of p38 MAP kinase.Bioorg Med Chem Lett. 2006 Dec 15;16(24):6316-20. doi: 10.1016/j.bmcl.2006.09.014. Epub 2006 Sep 28. Bioorg Med Chem Lett. 2006. PMID: 17010605
-
Discovery and optimization of p38 inhibitors via computer-assisted drug design.J Med Chem. 2007 Aug 23;50(17):4016-26. doi: 10.1021/jm070415w. Epub 2007 Jul 20. J Med Chem. 2007. PMID: 17658737
-
Fragment-based drug discovery.J Med Chem. 2004 Jul 1;47(14):3463-82. doi: 10.1021/jm040031v. J Med Chem. 2004. PMID: 15214773 Review. No abstract available.
-
New therapeutic targets in cardiology: p38 alpha mitogen-activated protein kinase for ischemic heart disease.Circulation. 2012 Jul 17;126(3):357-68. doi: 10.1161/CIRCULATIONAHA.111.071886. Circulation. 2012. PMID: 22801653 Review. No abstract available.
Cited by
-
NMR Characterization of Information Flow and Allosteric Communities in the MAP Kinase p38γ.Sci Rep. 2016 Jun 29;6:28655. doi: 10.1038/srep28655. Sci Rep. 2016. PMID: 27353957 Free PMC article.
-
Potential Mean Force from Umbrella Sampling Simulations: What Can We Learn and What Is Missed?J Chem Theory Comput. 2019 Apr 9;15(4):2433-2443. doi: 10.1021/acs.jctc.8b01142. Epub 2019 Mar 14. J Chem Theory Comput. 2019. PMID: 30811931 Free PMC article.
-
Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases.Elife. 2017 Feb 6;6:e21137. doi: 10.7554/eLife.21137. Elife. 2017. PMID: 28166054 Free PMC article.
-
Role of Molecular Interactions and Protein Rearrangement in the Dissociation Kinetics of p38α MAP Kinase Type-I/II/III Inhibitors.J Chem Inf Model. 2018 May 29;58(5):968-981. doi: 10.1021/acs.jcim.7b00640. Epub 2018 Apr 16. J Chem Inf Model. 2018. PMID: 29620886 Free PMC article.
-
The feasibility of parameterizing four-state equilibria using relaxation dispersion measurements.J Biomol NMR. 2011 Sep;51(1-2):57-70. doi: 10.1007/s10858-011-9541-1. Epub 2011 Sep 27. J Biomol NMR. 2011. PMID: 21947915 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources