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. 1992 Jul;127(1):18-21.
doi: 10.1111/j.1365-2133.1992.tb14818.x.

Smoking habits in psoriasis: a case control study

C M Mills  1 , E D Srivastava, I M Harvey, G L Swift, R G Newcombe, P J Holt, J Rhodes
Affiliations

Smoking habits in psoriasis: a case control study

C M Mills et al. Br J Dermatol. 1992 Jul.

Abstract

We have examined smoking habits in 108 patients with psoriasis, including some with palmoplantar distribution, and compared the results with matched controls from the community. There was a significant association between psoriasis, current smoking status (OR = 2.7, 95% CI 1.44-5.42, P less than 0.01) and smoking habits prior to the onset of disease (OR = 3.75, 95% CI 1.68-9.47, P less than 0.001). There was also a marked dose-response relationship; the relative risk of psoriasis in those currently smoking more than 20 cigarettes/day was significantly elevated (OR = 5.3, 95% CI 2.1-13.0, P less than 0.001). Separate analysis of patients without palmoplantar distribution of psoriasis showed a significant association with smoking prior to onset of psoriasis (OR = 3.6, 95% CI 1.5-9.8, P less than 0.001). Smoking may play a role in the aetiology of this common skin disorder.

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Comment in

  • Smoking, drinking and psoriasis.
    Higgins EM, Peters TJ, du Vivier AW. Higgins EM, et al. Br J Dermatol. 1993 Dec;129(6):749-50. doi: 10.1111/j.1365-2133.1993.tb03349.x. Br J Dermatol. 1993. PMID: 8286268 No abstract available.