Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1992 Jun;6(3):267-71.
doi: 10.1007/BF00051149.

Hibernating myocardium: a historical perspective

J F Tubau  1 , S H Rahimtoola
Affiliations
Review

Hibernating myocardium: a historical perspective

J F Tubau et al. Cardiovasc Drugs Ther. 1992 Jun.

Abstract

Hibernating myocardium refers to the presence of persistent myocardial and left ventricular dysfunction at rest, associated with conditions of severely reduced coronary blood flow. This left ventricular dysfunction probably represents an adaptive mechanism preventing irreversible myocardial cell damage, since myocardial and left ventricular dysfunction in hibernating myocardium improve following the restoration of coronary blood flow. This review examines the evolution of the concept of hibernation from a clinical observation of the potential underlying mechanisms recently proposed.

PubMed Disclaimer

References

    1. Circ Res. 1974 Dec;35(6):896-908 - PubMed
    1. Circulation. 1973 Feb;47(2):276-86 - PubMed
    1. Am J Cardiol. 1969 Apr;23 (4):538-47 - PubMed
    1. Circulation. 1991 Mar;83(3):1076-83 - PubMed
    1. Am Heart J. 1989 Jan;117(1):211-21 - PubMed

Substances