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Review
. 2006 Feb;18(1):68-73.
doi: 10.1016/j.ceb.2005.12.014. Epub 2005 Dec 27.

Walking with myosin V

James R Sellers  1 , Claudia Veigel
Affiliations
Review

Walking with myosin V

James R Sellers et al. Curr Opin Cell Biol. 2006 Feb.

Abstract

The cytoplasm of cells is teaming with vesicles and other cargo that are moving along tracks of microtubules or actin filaments, powered by myosins, kinesins and dyneins. Myosin V has been implicated in several types of intracellular transport. The mechanism by which myosin V moves processively along actin filaments has been the subject of many biophysical and biochemical studies and a consensus is starting to emerge about how this minute molecular motor operates.

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