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Review
. 1992 Apr;2(2):205-10.
doi: 10.1016/s0959-437x(05)80275-8.

Structure of the leucine zipper

T Alber  1
Affiliations
Review

Structure of the leucine zipper

T Alber. Curr Opin Genet Dev. 1992 Apr.

Abstract

In the basic-region leucine-zipper domain, flexible DNA-binding arms are juxtaposed by a two-stranded, parallel coiled-coil motif called the leucine zipper. Genetic, physical and structural studies of the leucine zipper identify interactions that help determine the stability and specificity of dimerization and DNA binding.

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