Review
doi: 10.1016/s0959-437x(05)80275-8.
Structure of the leucine zipper
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- PMID: 1638114
- DOI: 10.1016/s0959-437x(05)80275-8
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Review
Structure of the leucine zipper
Curr Opin Genet Dev.
1992 Apr.
Abstract
In the basic-region leucine-zipper domain, flexible DNA-binding arms are juxtaposed by a two-stranded, parallel coiled-coil motif called the leucine zipper. Genetic, physical and structural studies of the leucine zipper identify interactions that help determine the stability and specificity of dimerization and DNA binding.
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