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. 2006 Jan 1;34(Database issue):D261-6.
doi: 10.1093/nar/gkj008.

The EROP-Moscow oligopeptide database

Affiliations

The EROP-Moscow oligopeptide database

Alexander A Zamyatnin et al. Nucleic Acids Res. .

Abstract

Natural oligopeptides may regulate nearly all vital processes. To date, the chemical structures of nearly 6000 oligopeptides have been identified from >1000 organisms representing all the biological kingdoms. We have compiled the known physical, chemical and biological properties of these oligopeptides--whether synthesized on ribosomes or by non-ribosomal enzymes--and have constructed an internet-accessible database, EROP-Moscow (Endogenous Regulatory OligoPeptides), which resides at http://erop.inbi.ras.ru. This database enables users to perform rapid searches via many key features of the oligopeptides, and to carry out statistical analysis of all the available information. The database lists only those oligopeptides whose chemical structures have been completely determined (directly or by translation from nucleotide sequences). It provides extensive links with the Swiss-Prot-TrEMBL peptide-protein database, as well as with the PubMed biomedical bibliographic database. EROP-Moscow also contains data on many oligopeptides that are absent from other convenient databases, and is designed for extended use in classifying new natural oligopeptides and for production of novel peptide pharmaceuticals.

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Figures

Figure 1
Figure 1
EROP-Moscow architecture illustrated on the Site Map page.
Figure 2
Figure 2
Increase in the number of decoded amino acid sequences of the natural oligopeptides (Statistics page 1).
Figure 3
Figure 3
Distribution of known oligopeptides by amino acid residue number (Statistics page 2).

References

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