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. 2006 Jan 1;34(Database issue):D95-7.
doi: 10.1093/nar/gkj115.

A new generation of JASPAR, the open-access repository for transcription factor binding site profiles

Dominique Vlieghe  1 , Albin Sandelin, Pieter J De Bleser, Kris Vleminckx, Wyeth W Wasserman, Frans van Roy, Boris Lenhard
Affiliations

A new generation of JASPAR, the open-access repository for transcription factor binding site profiles

Dominique Vlieghe et al. Nucleic Acids Res. .

Abstract

JASPAR is the most complete open-access collection of transcription factor binding site (TFBS) matrices. In this new release, JASPAR grows into a meta-database of collections of TFBS models derived by diverse approaches. We present JASPAR CORE--an expanded version of the original, non-redundant collection of annotated, high-quality matrix-based transcription factor binding profiles, JASPAR FAM--a collection of familial TFBS models and JASPAR phyloFACTS--a set of matrices computationally derived from statistically overrepresented, evolutionarily conserved regulatory region motifs from mammalian genomes. JASPAR phyloFACTS serves as a non-redundant extension to JASPAR CORE, enhancing the overall breadth of JASPAR for promoter sequence analysis. The new release of JASPAR is available at http://jaspar.genereg.net.

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