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. 2006 Jan;54(1):61-3.
doi: 10.1016/j.jaad.2005.10.006.

The efficacy of multiple courses of alefacept in patients with moderate to severe chronic plaque psoriasis

Alan Menter  1 , Jennifer C Cather, Diane Baker, Harold F Farber, Mark Lebwohl, Mohamed Darif
Affiliations

The efficacy of multiple courses of alefacept in patients with moderate to severe chronic plaque psoriasis

Alan Menter et al. J Am Acad Dermatol. 2006 Jan.

Abstract

Among patients with psoriasis who did not achieve Psoriasis Area and Severity Index 50 during the first course of alefacept therapy, 53% achieved Psoriasis Area and Severity Index 50 during the second course (odds ratio [95% confidence interval] vs placebo 2.30 [1.26-4.19]). Alefacept provided incremental efficacy over 5 successive 12-week treatment courses.

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Comment in

  • On multiple courses of alefacept.
    Leonardi CL, Strober BE. Leonardi CL, et al. J Am Acad Dermatol. 2006 Nov;55(5):916-7. doi: 10.1016/j.jaad.2006.04.075. J Am Acad Dermatol. 2006. PMID: 17052512 No abstract available.

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