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Review
. 2006 Dec;92(12):1724-7.
doi: 10.1136/hrt.2005.066878. Epub 2005 Dec 30.

Connexin 43 signalling and cardioprotection

K Boengler  1 , R Schulz, G Heusch
Affiliations
Review

Connexin 43 signalling and cardioprotection

K Boengler et al. Heart. 2006 Dec.

Abstract

Connexin (Cx) 43 is the predominant protein forming gap junctions and non-junctional hemichannels in ventricular myocardium. The Cx43 proteins are central to the cardioprotection afforded by ischaemic preconditioning (IP). The specific role of mitochondrial Cx43 in protection by IP is reviewed.

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