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Controlled Clinical Trial
. 2005 Sep;23(6):391-7.

Clinical evaluation of pulmonary nodules with dual-exposure dual-energy subtraction chest radiography

Affiliations
  • PMID: 16389980
Controlled Clinical Trial

Clinical evaluation of pulmonary nodules with dual-exposure dual-energy subtraction chest radiography

Masahiko Uemura et al. Radiat Med. 2005 Sep.

Abstract

Purpose: The purpose of this study was to assess the effect of dual-exposure dual-energy (DE) subtraction chest radiography with flat-panel detector.

Materials and methods: One hundred patients underwent dual-exposure DE subtraction chest radiography and chest CT for evaluation of pulmonary nodules. Fifty-two patients with pulmonary nodules and 48 patients with normal lungs were selected for receiver operating characteristic (ROC) curve analysis. Ten radiologists who were unaware of the CT results evaluated chest radiography alone and chest radiography with DE subtraction images in the detection of pulmonary nodules. For each radiologist, we calculated the areas under the ROC curve (Az) for chest radiography alone and chest radiography with DE subtraction images.

Results: The average detectability of dual-exposure DE subtraction chest radiography was statistically significantly higher than that of chest radiography without subtraction images (mean Az value increased from 0.784 to 0.815, p<0.001).

Conclusion: Dual-exposure DE subtraction chest radiography improves diagnostic accuracy of pulmonary nodules.

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