doi: 10.1021/ja0571794.
Total synthesis of ecteinascidin 743
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- PMID: 16390134
- DOI: 10.1021/ja0571794
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Total synthesis of ecteinascidin 743
J Am Chem Soc.
.
Abstract
A convergent total synthesis of ecteinascidin 743 is realized from five building blocks of almost equal size. It takes 23 steps from l-3-hydroxy-4-methoxy-5-methyl phenylalanol (5) with an overall yield of 3%.
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