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Comparative Study
. 2006 Jan;44(1):251-3.
doi: 10.1128/JCM.44.1.251-253.2006.

Rapid, noninvasive diagnosis of visceral leishmaniasis in India: comparison of two immunochromatographic strip tests for detection of anti-K39 antibody

Shyam Sundar  1 , Radheshyam Maurya, Rakesh K Singh, K Bharti, Jaya Chakravarty, Ashish Parekh, Madhukar Rai, Kailash Kumar, Henry W Murray
Affiliations
Comparative Study

Rapid, noninvasive diagnosis of visceral leishmaniasis in India: comparison of two immunochromatographic strip tests for detection of anti-K39 antibody

Shyam Sundar et al. J Clin Microbiol. 2006 Jan.

Abstract

Used with blood or serum, a new anti-K39 antibody immunochromatographic strip test (IT-Leish; DiaMed AG) proved sensitive (range, 99 to 100%) and specific (range, 95 to 100%) for the noninvasive serodiagnosis of visceral leishmaniasis in India. Used with serum, the IT-Leish test and the existing Kalazar Detect test (InBios International, Inc.) yielded comparable results for symptomatic infection and identified apparent subclinical infection in 15 to 32% of healthy residents in a region where visceral leishmaniasis is highly endemic.

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