Remodelling epithelial tubes through cell rearrangements: from cells to molecules
- PMID: 16391535
- PMCID: PMC1369232
- DOI: 10.1038/sj.embor.7400597
Remodelling epithelial tubes through cell rearrangements: from cells to molecules
Abstract
Epithelial cell movements, such as those that occur during cell intercalation, largely contribute to the formation of epithelial structures during the morphogenesis of multicellular organisms. As the architecture of epithelial tissues relies on strong adhesion between cells at adherens junctions (AJs), the intercalation or rearrangements of epithelial cells might be controlled by modulating the adhesion dynamics of the AJs by internal or external forces. In this review, we describe recent progress in understanding cell rearrangements during epithelial tube remodelling and discuss several models that might account for the developmental control of the spatial dynamics of AJs.
Figures



Similar articles
-
Mechanical Force-Driven Adherens Junction Remodeling and Epithelial Dynamics.Dev Cell. 2018 Oct 8;47(1):3-19. doi: 10.1016/j.devcel.2018.09.014. Dev Cell. 2018. PMID: 30300588 Review.
-
Dynamics and regulation of epithelial adherens junctions: recent discoveries and controversies.Int Rev Cell Mol Biol. 2013;303:27-99. doi: 10.1016/B978-0-12-407697-6.00002-7. Int Rev Cell Mol Biol. 2013. PMID: 23445808 Review.
-
Genetic control of cell intercalation during tracheal morphogenesis in Drosophila.Curr Biol. 2004 Dec 29;14(24):2197-207. doi: 10.1016/j.cub.2004.11.056. Curr Biol. 2004. PMID: 15620646
-
Control of polarized cell morphology and motility by adherens junctions.Semin Cell Dev Biol. 2011 Oct;22(8):850-7. doi: 10.1016/j.semcdb.2011.07.023. Epub 2011 Aug 4. Semin Cell Dev Biol. 2011. PMID: 21839846 Review.
-
Adherens junctions and cadherins in Drosophila development.Subcell Biochem. 2012;60:251-77. doi: 10.1007/978-94-007-4186-7_11. Subcell Biochem. 2012. PMID: 22674075 Review.
Cited by
-
The Flagellum Attachment Zone: 'The Cellular Ruler' of Trypanosome Morphology.Trends Parasitol. 2016 Apr;32(4):309-324. doi: 10.1016/j.pt.2015.12.010. Epub 2016 Jan 8. Trends Parasitol. 2016. PMID: 26776656 Free PMC article. Review.
-
Unravelling the distinct contribution of cell shape changes and cell intercalation to tissue morphogenesis: the case of the Drosophila trachea.Open Biol. 2020 Nov;10(11):200329. doi: 10.1098/rsob.200329. Epub 2020 Nov 25. Open Biol. 2020. PMID: 33234070 Free PMC article.
-
Conditional switches for extracellular matrix patterning in Drosophila melanogaster.Genetics. 2008 Mar;178(3):1283-93. doi: 10.1534/genetics.106.065912. Epub 2008 Feb 3. Genetics. 2008. PMID: 18245854 Free PMC article.
-
The temporal basis of angiogenesis.Philos Trans R Soc Lond B Biol Sci. 2017 May 19;372(1720):20150522. doi: 10.1098/rstb.2015.0522. Philos Trans R Soc Lond B Biol Sci. 2017. PMID: 28348255 Free PMC article. Review.
-
An Atlas of Transcription Factors Expressed in Male Pupal Terminalia of Drosophila melanogaster.G3 (Bethesda). 2019 Dec 3;9(12):3961-3972. doi: 10.1534/g3.119.400788. G3 (Bethesda). 2019. PMID: 31619460 Free PMC article.
References
-
- Affolter M, Bellusci S, Itoh N, Shilo B, Thiery JP, Werb Z (2003) Tube or not tube: remodeling epithelial tissues by branching morphogenesis. Dev Cell 4: 11–18 - PubMed
-
- Bauer R, Loer B, Ostrowski K, Martini J, Weimbs A, Lechner H, Hoch M (2005) Intercellular communication: the Drosophila innexin multiprotein family of gap junction proteins. Chem Biol 12: 515–526 - PubMed
-
- Beloussov LV, Louchinskaia NN, Stein AA (2000) Tension-dependent collective cell movements in the early gastrula ectoderm of Xenopus laevis embryos. Dev Genes Evol 210: 92–104 - PubMed
-
- Bertet C, Sulak L, Lecuit T (2004) Myosin-dependent junction remodelling controls planar cell intercalation and axis elongation. Nature 429: 667–671 - PubMed
-
- Bryant DM, Stow JL (2004) The ins and outs of E-cadherin trafficking. Trends Cell Biol 14: 427–434 - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Molecular Biology Databases
Research Materials