doi: 10.1016/0888-7543(92)90133-d.
Isolation and chromosomal assignment of 100 highly informative human simple sequence repeat polymorphisms
Affiliations
- PMID: 1639389
- DOI: 10.1016/0888-7543(92)90133-d
Item in Clipboard
Isolation and chromosomal assignment of 100 highly informative human simple sequence repeat polymorphisms
Genomics.
1992 Jul.
Abstract
One hundred highly informative simple sequence repeat (SSR) polymorphisms have been isolated and mapped to specific human chromosomes by somatic cell hybrid analysis. These markers include 97 (CA)n, 2 (AGAT)n, and a single (AACT)n repeat. All the SSRs have heterozygosities greater than 0.50 and can be amplified using identical PCR conditions. At least one SSR was detected on every chromosome, except for chromosomes 22 and Y. The frequency of (CA)n repeats on each chromosome was proportional to the relative chromosomal length, except for chromosome 15, on which a substantial excess of markers was identified.
Similar articles
-
Three CA/GT repeat polymorphisms from loci D21S414 and D21S1234 on human chromosome 21.Hum Genet. 1994 Mar;93(3):359-60. doi: 10.1007/BF00212043. Hum Genet. 1994. PMID: 8125493
-
Isolation and mapping of three new polymorphic markers to chromosomes 3, 20 and 21.Ann Hum Genet. 1996 Jan;60(1):73-7. doi: 10.1111/j.1469-1809.1996.tb01174.x. Ann Hum Genet. 1996. PMID: 8835101
-
Linkage mapping of D21S171 to the distal long arm of human chromosome 21 using a polymorphic (AC)n dinucleotide repeat.Hum Genet. 1991 Aug;87(4):401-4. doi: 10.1007/BF00197156. Hum Genet. 1991. PMID: 1879826
-
Genetic marker technology.Curr Opin Biotechnol. 1991 Dec;2(6):818-22. doi: 10.1016/s0958-1669(05)80113-2. Curr Opin Biotechnol. 1991. PMID: 1367954 Review.
-
On the essence of "meaningless" simple repetitive DNA in eukaryote genomes.EXS. 1993;67:29-45. doi: 10.1007/978-3-0348-8583-6_3. EXS. 1993. PMID: 8400700 Review.
Cited by
-
SMN gene analysis of the spinal form of Charcot-Marie-Tooth disease.J Med Genet. 1997 Jun;34(6):507-8. doi: 10.1136/jmg.34.6.507. J Med Genet. 1997. PMID: 9192274 Free PMC article.
-
An extra cysteine in one of the non-calcium-binding epidermal growth factor-like motifs of the FBN1 polypeptide is connected to a novel variant of Marfan syndrome.J Clin Invest. 1994 Aug;94(2):709-13. doi: 10.1172/JCI117389. J Clin Invest. 1994. PMID: 8040326 Free PMC article.
-
Sporadic imprinting defects in Prader-Willi syndrome and Angelman syndrome: implications for imprint-switch models, genetic counseling, and prenatal diagnosis.Am J Hum Genet. 1998 Jul;63(1):170-80. doi: 10.1086/301935. Am J Hum Genet. 1998. PMID: 9634532 Free PMC article.
-
A molecular and cytogenetic study in Finnish Prader-Willi patients.Hum Genet. 1995 May;95(5):568-71. doi: 10.1007/BF00223871. Hum Genet. 1995. PMID: 7759080
-
Mapping of two new markers within the smallest interval harboring the spinal muscular atrophy locus by family and radiation hybrid analysis.Hum Genet. 1994 May;93(5):494-501. doi: 10.1007/BF00202811. Hum Genet. 1994. PMID: 8168823
Publication types
MeSH terms
Substances
Associated data
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Research Materials
Miscellaneous
