Drosha versus ADAR: wrangling over pri-miRNA
- PMID: 16395313
- DOI: 10.1038/nsmb0106-3
Drosha versus ADAR: wrangling over pri-miRNA
Abstract
Processing of a mammalian hematopoietic microRNA precursor is suppressed when it is edited by ADARs. The edited pri-miRNA can subsequently be degraded by Tudor-SN.
Comment on
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Modulation of microRNA processing and expression through RNA editing by ADAR deaminases.Nat Struct Mol Biol. 2006 Jan;13(1):13-21. doi: 10.1038/nsmb1041. Epub 2005 Dec 20. Nat Struct Mol Biol. 2006. PMID: 16369484 Free PMC article.
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