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Comment
. 2006 Jan;13(1):5-7.
doi: 10.1038/nsmb0106-5.

Chromatin, transcript elongation and alternative splicing

Comment

Chromatin, transcript elongation and alternative splicing

Alberto R Kornblihtt. Nat Struct Mol Biol. 2006 Jan.

Abstract

A recent study reveals that the chromatin-remodeling factor SWI/SNF regulates alternative splicing by creating internal 'roadblocks' to transcriptional elongation where the phosphorylation status of RNA pol II is qualitatively changed.

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