Skeletal muscle weakness, reduced exercise tolerance, and COPD: is systemic inflammation the missing link?
- PMID: 16396949
- PMCID: PMC2080700
- DOI: 10.1136/thx.2005.044941
Skeletal muscle weakness, reduced exercise tolerance, and COPD: is systemic inflammation the missing link?
Abstract
Systemic inflammation may be the “missing link” between airway dysfunction and the extrapulmonary manifestations of COPD
Conflict of interest statement
Conflict of interest: The authors have received honoraria for speaking engagements from GlaxoSmithKline (GSK) and AstraZeneca and for consultative services from GSK. They have also received research funding from GSK.
Comment on
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Raised CRP levels mark metabolic and functional impairment in advanced COPD.Thorax. 2006 Jan;61(1):17-22. doi: 10.1136/thx.2005.041996. Epub 2005 Jul 29. Thorax. 2006. PMID: 16055618 Free PMC article.
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C-reactive protein in patients with COPD, control smokers and non-smokers.Thorax. 2006 Jan;61(1):23-8. doi: 10.1136/thx.2005.042200. Epub 2005 Sep 2. Thorax. 2006. PMID: 16143583 Free PMC article.
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Inflammatory markers are associated with ventilatory limitation and muscle dysfunction in obstructive lung disease in well functioning elderly subjects.Thorax. 2006 Jan;61(1):10-6. doi: 10.1136/thx.2004.034181. Epub 2005 Nov 11. Thorax. 2006. PMID: 16284220 Free PMC article.
References
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- Sin D D, Wu L, Man S F. The relationship between reduced lung function and cardiovascular mortality: a population‐based study and a systematic review of the literature. Chest 20051271952–1959. - PubMed
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