doi: 10.1038/253507a0.
Ethidium bromide inhibits appearance of closed circular viral DNA and integration of virus-specific DNA in duck cells infected by avian sarcoma virus
- PMID: 163973
- DOI: 10.1038/253507a0
Item in Clipboard
Ethidium bromide inhibits appearance of closed circular viral DNA and integration of virus-specific DNA in duck cells infected by avian sarcoma virus
Nature.
.
Abstract
The DNA of avian sarcoma virus assumes a closed circular configuration before integration into the host cell chromosomal DNA. Ethidium bromide reduces the formation of superhelical viral DNA and concurrently blocks integration of the viral genome. Inhibition of integration of viral DNA results in the inhibition of virus replication.
Similar articles
-
Synthesis, structure and function of avian sarcoma virus-specific DNA in permissive and nonpermissive cells.Cold Spring Harb Symp Quant Biol. 1975;39 Pt 2:987-96. doi: 10.1101/sqb.1974.039.01.113. Cold Spring Harb Symp Quant Biol. 1975. PMID: 50903
-
Synthesis of viral DNA in the cytoplasm of duck embryo fibroblasts and in enucleated cells after infection by avian sarcoma virus.Proc Natl Acad Sci U S A. 1974 Oct;71(10):3874-8. doi: 10.1073/pnas.71.10.3874. Proc Natl Acad Sci U S A. 1974. PMID: 4372595 Free PMC article.
-
Covalently closed circular DNA of avian sarcoma virus: purification from nuclei of infected quail tumor cells and measurement by electron microscopy and gel electrophoresis.J Mol Biol. 1976 Sep 15;106(2):337-57. doi: 10.1016/0022-2836(76)90090-5. J Mol Biol. 1976. PMID: 185393 No abstract available.
-
SV40 DNA: quantitative conversion of closed circular to open circular form by an ethidium bromide-restricted endonuclease.J Mol Biol. 1973 Mar 15;74(4):739-42. doi: 10.1016/0022-2836(73)90062-4. J Mol Biol. 1973. PMID: 4354078 No abstract available.
-
DNA intermediates of avian RNA tumor viruses.Curr Top Microbiol Immunol. 1979;87:23-41. doi: 10.1007/978-3-642-67344-3_2. Curr Top Microbiol Immunol. 1979. PMID: 232870 Review. No abstract available.
Cited by
-
Production of avian oncoviral subgroups after multiple infection.J Virol. 1979 Mar;29(3):926-37. doi: 10.1128/JVI.29.3.926-937.1979. J Virol. 1979. PMID: 221681 Free PMC article.
-
Isolation and characterization of recombinant DNA clones of avian retroviruses: size heterogeneity and instability of the direct repeat.J Virol. 1980 Mar;33(3):1026-33. doi: 10.1128/JVI.33.3.1026-1033.1980. J Virol. 1980. PMID: 6245258 Free PMC article.
-
Murine mammary tumor virus: characterization of infection of nonmurine cells.J Virol. 1976 Jun;18(3):911-7. doi: 10.1128/JVI.18.3.911-917.1976. J Virol. 1976. PMID: 178928 Free PMC article.
-
Virus-specific DNA in the cytoplasm of avian sarcoma virus-infected cells is a precursor to covalently closed circular viral DNA in the nucleus.J Virol. 1978 Jan;25(1):104-4. doi: 10.1128/JVI.25.1.104-104.1978. J Virol. 1978. PMID: 202729 Free PMC article.
-
Production of unintegrated mouse mammary tumor virus DNA in infected rat hepatoma cells is a secondary action of dexamethasone.J Virol. 1978 Apr;26(1):93-101. doi: 10.1128/JVI.26.1.93-101.1978. J Virol. 1978. PMID: 206732 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
