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. 2006 Jan;147 Suppl 1(Suppl 1):S120-6.
doi: 10.1038/sj.bjp.0706474.

Acetylcholine

David A Brown  1
Affiliations

Acetylcholine

David A Brown. Br J Pharmacol. 2006 Jan.

Abstract

This article traces the development of knowledge about the physiology and pharmacology of acetylcholine and its receptors between 1930 and 2005, with emphasis on contributions by members of the British Pharmacological Society, and by other British pharmacologists and physiologists.

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Figures

Figure 1
Figure 1
Some U.K. cholinergic pharmacological luminaries. (a) H.H. Dale; (b) W. Feldberg; (c) W.D.M. Paton. Photographs © the Royal Society.
Figure 2
Figure 2
Summary of the main pharmacological actions of the bistrimethylammonium series. Abscissa: number of carbon atoms in polymethylene chain. Ordinate: logarithmic scale of potency, with arbitrary origins (from Paton & Zaimis (1949), with permission).
See this image and copyright information in PMC

References

    1. ADAMS P.R., BROWN D.A. Synaptic inhibition of the M-current: slow excitatory post-synaptic potential mechanism in bullfrog sympathetic neurones. J. Physiol. 1982;332:263–272. - PMC - PubMed
    1. ALEXANDER S.P.H., MATHIE A., PETERS J.A. Acetylcholine (muscarinic) receptors: guide to receptors and channels. Br. J. Pharmacol. 2004;141:S6. - PMC - PubMed
    1. ALLEN T.G., BROWN D.A. Detection and modulation of acetylcholine release from neurites of rat basal forebrain cells in culture. J. Physiol. 1996;492:453–466. - PMC - PubMed
    1. ARMITAGE A.K., MILTON A.S., MORRISON C.F. Effects of nicotine and some nicotine-like compounds injected into the cerebral ventricles of the cat. Br. J. Pharmacol. Chemother. 1966;27:33–45. - PMC - PubMed
    1. BERRIE C.P., BIRDSALL N.J., HULME E.C., KEEN M., STOCKTON J.M. Solubilization and characterization of high and low affinity pirenzepine binding sites from rat cerebral cortex. Br. J. Pharmacol. 1985;85:697–703. - PMC - PubMed