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. 2005 Dec;49(4):582-4.
doi: 10.1637/7364-041105R.1.

Experimental assessment of the pathogenicity of H5N1 influenza A viruses isolated in Japan

Masaji Mase  1 , Tadao Imada, Kikuyasu Nakamura, Nobuhiko Tanimura, Kunitoshi Imai, Kenji Tsukamoto, Shigeo Yamaguchi
Affiliations

Experimental assessment of the pathogenicity of H5N1 influenza A viruses isolated in Japan

Masaji Mase et al. Avian Dis. 2005 Dec.

Abstract

We examined the pathogenicity for chickens of two H5N1 avian influenza viruses isolated in Japan, A/chicken/ Yamaguchi/7/2004 (Ck/Yamaguchi/7/04) isolated from outbreaks in commercial layer chickens, and A/duck/Yokohama/aq10/ 2003 (Dk/Yokohama/aq10/03) isolated from duck meat imported from China. All chickens inoculated intranasally with either strain died, and the viruses were reisolated from all organs examined. However, both the mean time of onset of clinical signs and the mean death time of Ck/Yamaguchi/7/04 were shorter than those of Dk/Yokohama/aq10/03.

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