[Autoimmune haemopoietic disturbances simultaneous with autoimmune thyroid diseases]

Abstract

Out of 362 patients with diagnosis of autoimmune haemopathy treated in eight-year period at the Hematology centre, concomitant autoimmune thyreoideopathy was confirmed in 22 (5.52%). The most frequent was simultaneous manifestation of pernicious anemia and autoimmune thyreoiditis-Phenomenon was less frequently observed in patients with immune thrombocytopenic purpura and Graves disease. In the subgroup of patients with autoimmune hemolytic anemia, there was no evidence of simultaneous autoimmune thyreoideopathy. General opinion is that etiopathogenesis of these immunological disorders does not include unique mechanism of humoral and cellular immune response; more probable, it is the question of normal immune response regulation impairment, based on the paerticular genetic predisposition.