doi: 10.1038/nchembio0705-71.
Relaxed specificity in aromatic prenyltransferases
- PMID: 16408001
- DOI: 10.1038/nchembio0705-71
Item in Clipboard
Relaxed specificity in aromatic prenyltransferases
Nat Chem Biol.
2005 Jul.
Abstract
Prenylation represent a critical step in the biosynthesis of many natural products, A new study reveals how aromatic prenyltransferase enzymes tolerate diverse aromatic polyketides while still controlling the length of prenyl side chains.
Similar articles
-
Novel prenyltransferase enzymes as a tool for flavonoid prenylation.Trends Pharmacol Sci. 2005 Dec;26(12):606-8. doi: 10.1016/j.tips.2005.09.012. Epub 2005 Oct 17. Trends Pharmacol Sci. 2005. PMID: 16229901
-
Structure and mechanism of the magnesium-independent aromatic prenyltransferase CloQ from the clorobiocin biosynthetic pathway.J Mol Biol. 2010 Dec 10;404(4):611-26. doi: 10.1016/j.jmb.2010.09.067. Epub 2010 Oct 12. J Mol Biol. 2010. PMID: 20946900
-
Diversity of ABBA Prenyltransferases in Marine Streptomyces sp. CNQ-509: Promiscuous Enzymes for the Biosynthesis of Mixed Terpenoid Compounds.PLoS One. 2015 Dec 14;10(12):e0143237. doi: 10.1371/journal.pone.0143237. eCollection 2015. PLoS One. 2015. PMID: 26659564 Free PMC article.
-
Structure and function of cis-prenyl chain elongating enzymes.Chem Rec. 2006;6(4):194-205. doi: 10.1002/tcr.20083. Chem Rec. 2006. PMID: 16900467 Review.
-
Molecular and structural basis of metabolic diversity mediated by prenyldiphosphate converting enzymes.Phytochemistry. 2009 Oct-Nov;70(15-16):1758-75. doi: 10.1016/j.phytochem.2009.09.001. Epub 2009 Oct 29. Phytochemistry. 2009. PMID: 19878958 Review.
Cited by
-
A soluble, magnesium-independent prenyltransferase catalyzes reverse and regular C-prenylations and O-prenylations of aromatic substrates.FEBS Lett. 2007 Jun 26;581(16):2889-93. doi: 10.1016/j.febslet.2007.05.031. Epub 2007 May 22. FEBS Lett. 2007. PMID: 17543953 Free PMC article.
-
Biosynthesis of Nature-Inspired Unnatural Cannabinoids.Molecules. 2021 May 14;26(10):2914. doi: 10.3390/molecules26102914. Molecules. 2021. PMID: 34068935 Free PMC article. Review.
-
A new group of aromatic prenyltransferases in fungi, catalyzing a 2,7-dihydroxynaphthalene 3-dimethylallyl-transferase reaction.J Biol Chem. 2010 May 28;285(22):16487-94. doi: 10.1074/jbc.M110.113720. Epub 2010 Mar 29. J Biol Chem. 2010. PMID: 20351110 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
