[Drug-induced pulmonary damage]
- PMID: 16408165
- DOI: 10.1007/s00292-005-0812-z
[Drug-induced pulmonary damage]
Abstract
The frequency of drug-induced damage to the lung in inpatients is estimated to be about 10%. Pathoanatomically, varying damage patterns result, ranging from acute pulmonary edema via inflammatory reactions to pulmonary fibrosis. The ATS/ERS 2001 classification, which is based on the suggestions made by Liebow 1969, is an accepted system for classifying findings according to recurring patterns. Generally, there are no specific morphological findings which allow safe conclusions on possible administered drugs. Clinical information is mandatory. Differentiation from pulmonary alterations due to the underlying disease is often difficult. In daily routine diagnostics, it is important to consider iatrogenic causal factors in cases of "undetermined pulmonary disease".
Similar articles
-
Drug-induced pulmonary disease. Part 2: Noncytotoxic drugs.Am Rev Respir Dis. 1986 Mar;133(3):488-505. doi: 10.1164/arrd.1986.133.3.488. Am Rev Respir Dis. 1986. PMID: 2869727 Review.
-
[Drug-induced lung diseases].Dtsch Med Wochenschr. 2011 Apr;136(13):631-4. doi: 10.1055/s-0031-1274553. Epub 2011 Mar 22. Dtsch Med Wochenschr. 2011. PMID: 21432739 Review. German.
-
Acute toxicity of irinotecan in the ex-vivo isolated perfused human lung model--high-dose therapy during isolated perfusion without acute toxic lung edema.Interact Cardiovasc Thorac Surg. 2007 Oct;6(5):583-7. doi: 10.1510/icvts.2007.152165. Epub 2007 Jul 4. Interact Cardiovasc Thorac Surg. 2007. PMID: 17670737
-
Ethyl pyruvate protects rats from phosgene-induced pulmonary edema by inhibiting cyclooxygenase2 and inducible nitric oxide synthase expression.J Appl Toxicol. 2013 Jan;33(1):71-7. doi: 10.1002/jat.1713. Epub 2011 Aug 5. J Appl Toxicol. 2013. PMID: 21818760
-
[Pulmonary toxicity of drugs and thoracic irradiation in children].Rev Mal Respir. 1996 Jul;13(3):235-42. Rev Mal Respir. 1996. PMID: 8765915 Review. French.
Cited by
-
[Drug-induced pulmonary diseases].Pneumologe (Berl). 2007;4(3):201-212. doi: 10.1007/s10405-007-0149-9. Epub 2007 Apr 26. Pneumologe (Berl). 2007. PMID: 32288714 Free PMC article. German.
-
[Drug-induced disorders of the lung parenchyma].Pneumologe (Berl). 2009;6(5):316-327. doi: 10.1007/s10405-008-0294-9. Epub 2009 Aug 1. Pneumologe (Berl). 2009. PMID: 32288716 Free PMC article. German.
References
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical