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. 1992 Jul 25;20(14):3763-72.
doi: 10.1093/nar/20.14.3763.

Sequence and variability of the 5.8S and 26S rRNA genes of Pneumocystis carinii

Y Liu  1 , M Rocourt, S Pan, C Liu, M J Leibowitz
Affiliations
Free PMC article

Sequence and variability of the 5.8S and 26S rRNA genes of Pneumocystis carinii

Y Liu et al. Nucleic Acids Res. .
Free PMC article

Abstract

The sequence of the coding region of the rRNA operon of rat-derived Pneumocystis carinii has been completed, including the genes for 5.8S and 26S rRNA. These genes show homology to the rRNA genes of yeast, and an apparent group I self-splicing intron is present in the 26S rRNA gene. Like a similar intron in the 16S rRNA gene, this intron is in a phylogenetically conserved region. Variation in the 26S rRNA sequence was noted between P. carinii organisms isolated from two different sources.

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