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Case Reports
. 1992 Jun;31(3):70-3.

[The detection of inflammation and the formation of HAMA following the administration of monoclonal antibody BW 250/183]

[Article in German]
R Berberich  1 , P Hennes, C Alexander
Affiliations
  • PMID: 1641357
Case Reports

[The detection of inflammation and the formation of HAMA following the administration of monoclonal antibody BW 250/183]

[Article in German]
R Berberich et al. Nuklearmedizin. 1992 Jun.

Abstract

Experiences with the use of the 99mTc-labelled MAb BW 250/183 in the detection of inflammatory lesions are reported. In 160 of 354 investigated patients the results could be confirmed by other methods. The sensitivity (91%) and the specificity (82%) were very high for a diagnostic tool and were comparable with the results of other leukocyte scans as reported in the literature. The positive predictive value of the method was 93%. In 84 patients studied once and in 6 patients studied twice only one case of the latter group showed a positive HAMA response. It may be concluded that the detection of foci of inflammation with the 99mTc-labelled MAb BW 250/183 is of great diagnostic value and that its administration can be repeated without risk.

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