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Comment
. 2006 Feb;80(3):1610-1; author reply 1611-2.
doi: 10.1128/JVI.80.3.1610-1612.2006.

Egress of alphaherpesviruses

Thomas C Mettenleiter, Tony Minson
Comment

Egress of alphaherpesviruses

Thomas C Mettenleiter et al. J Virol. 2006 Feb.
No abstract available

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Figures

FIG. 1.
FIG. 1.
Electron micrograph of BHK21 cells 12 h after infection with HSV-1. The arrow denotes an intact nuclear pore next to a capsid undergoing primary envelopment (left) and a primary enveloped virion in the perinuclear space (right). The nuclear side is on the top, and the cytoplasmic side is on the bottom. Bar, 500 nm. (Electron micrograph courtesy of Harald Granzow, Friedrich-Loeffler-Institut, Insel Riems, Germany).
FIG. 1.
FIG. 1.
HeLa cells grown on coverslips were infected with herpes simplex virus type 1 (multiplicity of infection of 2), incubated for 10 h, fixed with paraformaldehyde, and immunostained using monoclonal antibodies against nuclear pore complex proteins. Samples were analyzed using a confocal microscope, and images were deconvolved. (A) A mock-infected cell shows a rather regular distribution of nuclear pore complex proteins. (B) Nuclear pore complex proteins are accumulated at the nuclear surface and within the cytoplasm in a herpes simplex virus type 1-infected cell, clearly indicating dramatic changes of nuclear pores.
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References

    1. Fuchs, W., B. G. Klupp, H. Granzow, N. Osterrieder, and T. C. Mettenleiter. 2002. The interacting UL31 and Ul34 gene products of pseudorabies virus are involved in egress from the host cell nucleus and represent components of primary enveloped but not of mature virions. J. Virol. 76:364-378. - PMC - PubMed
    1. Granzow, H., B. G. Klupp, W. Fuchs, J. Veits, N. Osterrieder, and T. C. Mettenleiter. 2001. Egress of alphaherpesviruses: comparative ultrastructural study. J. Virol. 75:3675-3684. - PMC - PubMed
    1. Leuzinger, H., U. Ziegler, E. M. Schraner, C. Fraefel, D. L. Glauser, I. Heid, M. Ackermann, M. Mueller, and P. Wild. 2005. Herpes simplex virus type 1 envelopment follows two diverse pathways. J. Virol. 79:13047-13059. - PMC - PubMed
    1. Mettenleiter, T. C. 2002. Herpesvirus assembly and egress. J. Virol. 76:1537-1547. - PMC - PubMed
    1. Mettenleiter, T. C. 2004. Budding events in herpesvirus morphogenesis. Virus Res. 106:167-180. - PubMed

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