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. 1992 Aug;51(2):411-5.

Genetic linkage map of facioscapulohumeral muscular dystrophy and five polymorphic loci on chromosome 4q35-qter

C Wijmenga  1 , L A Sandkuijl, P Moerer, N van der Boorn, S E Bodrug, P N Ray, O F Brouwer, J C Murray, G J van Ommen, G W Padberg, et al.
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Genetic linkage map of facioscapulohumeral muscular dystrophy and five polymorphic loci on chromosome 4q35-qter

C Wijmenga et al. Am J Hum Genet. 1992 Aug.

Abstract

A genetic map of five polymorphic markers in the area of the facioscapulohumeral muscular dystrophy (FSHD) gene on chromosome 4q35-qter has been constructed. With these five markers, a number of recombinants have been identified that allow ordering of the marker and the disease loci. The most likely locus order and the relative position of the FSHD gene supported by the recombinants is centromere-D4S171-F11-D4S187-D4S163-D4S139-FS HD-telomere. However, at least one recombination event appears to be inconsistent with this order and suggests a location of FSHD proximal to D4S139.

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