Review
doi: 10.1016/j.autrev.2005.08.009.
Epub 2005 Sep 26.
Transcriptional repression of interleukin-2 in human systemic lupus erythematosus
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- PMID: 16431340
- DOI: 10.1016/j.autrev.2005.08.009
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Review
Transcriptional repression of interleukin-2 in human systemic lupus erythematosus
Autoimmun Rev.
2006 Feb.
Abstract
T cells from patients with SLE produce decreased amounts of interleukin-2 (IL-2), a central cytokine in the regulation of the immune response. We discuss herein the abnormalities underlying IL-2 deficiency in SLE T cells.
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