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Review
. 2006 Feb;5(2):118-21.
doi: 10.1016/j.autrev.2005.08.009. Epub 2005 Sep 26.

Transcriptional repression of interleukin-2 in human systemic lupus erythematosus

Christina G Katsiari  1 , George C Tsokos
Affiliations
Review

Transcriptional repression of interleukin-2 in human systemic lupus erythematosus

Christina G Katsiari et al. Autoimmun Rev. 2006 Feb.

Abstract

T cells from patients with SLE produce decreased amounts of interleukin-2 (IL-2), a central cytokine in the regulation of the immune response. We discuss herein the abnormalities underlying IL-2 deficiency in SLE T cells.

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