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Comment
. 2006 Jan 24;16(2):R51-3.
doi: 10.1016/j.cub.2006.01.008.

Tubulogenesis: an inside job

Lianna E Swanson  1 , Greg J Beitel
Affiliations
Comment

Tubulogenesis: an inside job

Lianna E Swanson et al. Curr Biol. .
No abstract available

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Figures

Figure 1
Figure 1
A model for tracheal tube-size control in Drosophila. Expansion of the tracheal tubes from narrow to larger diameters during late embryogenesis is regulated by a transient fibrillar chitin-based matrix (red) that is also required for normal organization of the apical βH spectrin cytoskeleton (blue). Septate junctions appear to mediate the apical secretion of Verm, which along with Serp is required for subsequent modification of this matrix to prevent the tracheal cells and tubes from becoming too long and, to a lesser extent, too large in diameter. Adapted from [1,2].
See this image and copyright information in PMC

Comment on

References

    1. Luschnig S, Baetz T, Armbruster K, Krasnow MA. serpentine and vermiform encode matrix proteins with chitin binding and deacetylation domains that limit tracheal tube length in Drosophila. Curr. Biol. 2006;16 this issue. - PubMed
    1. Wang S, Jayaram SA, Hemphala J, Senti KA, Tsarouhas V, Jin H, Samakovlis C. Septate junction dependent luminal deposition of chitin deacetylases restricts tube elongation in the Drosophila trachea. Curr. Biol. 2006;16 this issue. - PubMed
    1. Uv A, Cantera R, Samakovlis C. Drosophila tracheal morphogenesis: intricate cellular solutions to basic plumbing problems. Trends Cell Biol. 2003;13:301–309. - PubMed
    1. Araujo SJ, Aslam H, Tear G, Casanova J. mummy/cystic encodes an enzyme required for chitin and glycan synthesis, involved in trachea, embryonic cuticle and CNS development-Analysis of its role in Drosophila tracheal morphogenesis. Dev. Biol. 2005;288:179–193. - PubMed
    1. Moussian B, Schwarz H, Bartoszewski S, Nusslein-Volhard C. Involvement of chitin in exoskeleton morphogenesis in Drosophila melanogaster. J. Morphol. 2005;264:117–130. - PubMed

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